Despite the encouraging results regarding diffusion quantification in the discrimination of PCLs from both metastatic tumors and high-grade gliomas, there have been studies in the literature concluding that the contribution of DWI and DTI is insignificant in both the intratumoral [ 6, 8, 49, 107, 109] and peritumoral area [ 8, 10] of these lesions.
In case of technology risks, 'the incumbent operators are naturally favoring the harmonized approach (i.e. cooperation) since it decreases risks regarding the diffusion of the new technologies they have invested in and guarantees economies of the scale effects' [3].
Our study has theoretical implications regarding the diffusion of information and emotional contagion as well as practical implications for understanding how important information and social support can be effectively collected and distributed to populations in need.
The problem mentioned above plays an important role regarding to diffusion of fluid media containing nanoparticles, what is very useful in biomedical applications, such as artificial polymeric implants, drug delivery systems or tissue engineering.
Some delegations stressed the difficulties of developing countries regarding the diffusion of information and attendance at meetings and recalled that the views of countries which could not participate in the meetings should be taken into consideration.
The Greenhalgh model is based on a systematic review of the literature regarding the diffusion of innovations in health care organisations addressing the question: 'How can we spread and sustain innovations in health service delivery and organisations?' and identifies key domains in which factors influencing uptake and implementation are found.
Regarding the diffusion of the tumour, for which data were more complete, in most cases the metastases were multiple metastases beyond regional lymph nodes, both in typical sites (e.g., liver) and less typical sites (e.g., gastrointestinal tract), as well as some unusual sites (e.g., spinal cord).
However, a number of interesting observations emerged, partly regarding the way in which the diffusion is measured and partly regarding the actual diffusion of palliative care.
In our opinion, physical prerequisites regarding the diffusion threshold of 200 μm - 3.5 mm were met by the use of small cubic scaffolds with an edge length of 3 mm [ 21, 22].
