Regarding the study population's clinical characteristics in the multivariate model, intervention and ED setting were significant variables regarding a reduced risk of at least 1 PADE occurring per patient.
We consider a multivariate distribution function with regard to gene expression level x i and the genotype a. Considering that multiple genes are involved, we assume that the genotype is represented by a scalar parameter a (e.g., by a Hamming distance from the fittest genetic sequence).
Regarding overall survival, a multivariate analysis showed that the current real-time quantitative RT PCR technique using CEA and/or CK20 was an independent prognostic factor for the patients with a curative R0 resection.
Regarding emotional states a multivariate analysis of variance with group as fixed factor showed no significant differences concerning positive (PA; F 2,57) = 1.310, p = 0.278) and negative (NA; F 2,57) = 0.281, p = 0.756) mood.
Regarding the multivariate heritability studies, the log files (ACE, AE and E models) from OpenMx for MC, GC, CU and SI traits respectively are provided in Supplementary Files 17 20.
We thank Ute Hagner and Natalie Tissières for helping to conduct parts of the bioassays; John-Philip Lawo for advising us with the statistical methods used and Matthias Held for supporting us with the statistical software Canoco 4.5 and providing useful advice regarding the multivariate analysis.
Regarding covariates, multivariate analyses revealed no significant association between the standardized composite scales and gender, marital status, education level, hypertension, or smoking history.
Regarding forward stepwise multivariate analysis, the PET category remained as an independent predictor of CV event (Table 5).
Regarding the two multivariate approaches, the one using only the spectral index as covariate has provided better results in terms of unbiasedness and accuracy.
Regarding multivariate analysis, two different models were performed, not including or including the days on mechanical ventilation in the model.
