Well written manuscript regarding a controversial yet very important topic: the management of axial low back pain.
We wish to thank Tracey Easthope and Genevieve Howe of the Michigan Network for Children's Environmental Health, William Weil of Michigan State University and Ted Schettler of the Science Environmental Health Network for their comments regarding a draft of this manuscript.
After a closer look at Johnson's papers [22 24], we detected information regarding a further ten potential manuscripts of the Mappæ tradition, making a total of 25 witnesses.
Three anonymous reviewers provided useful advice regarding a previous version of the manuscript.
We thank Frank Miedema for valuable discussions, Morten Nielsen and Claus Lundegaard for extensive discussions on MHC-peptide binding predictions, Almut Scherer for valuable comments regarding an earlier version of the manuscript, and Frahm et al. [26] for making their dataset publicly available.
We are particularly grateful to our reviewers, especially Dr Lyndal Trevena, for their insightful comments regarding an earlier version of this manuscript.
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However, while the number of manuscripts reviewed and the time spent reviewing differed according to the time since first publication, there was no effect on the reported decision of a referee regarding manuscript rejection.
