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Processes within the course of severe sepsis and multiple organ failure have always been regarded as dysfunction at the cellular or organ level.
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The ACL-injured knee may constitute a suitable model for this approach, because this peripheral musculoskeletal injury may also be regarded as a neurophysiological dysfunction [ 27, 28].
Therefore, failure on the modified Romberg test from vestibular origin was defined as a state in which the participant passed test conditions 1 3 and did not pass test condition 4, and the participant was regarded as having vestibular dysfunction.
In case of ADHD, the functional impairment of attention performance is regarded as resulting from a dysfunction of frontal-cortical-networks.
Nowadays, the occurrence of a microcirculatory dysfunction is regarded as an important motor of sepsis-associated organ dysfunction [ 1- 4, 8].
A strong association was demonstrated between TDD incidence and various clinical factors, beyond antipsychotic medication, that were regarded as proxy measures for DA dysfunction in different tracts: high symptom severity scores, presence of sexual dysfunction, amenorrhea and EPS.
After all, either phenotype of chronic lung allograft dysfunction is regarded as chronic airway fibrosis (CAF).
Renal dysfunction is regarded as a confounding factor when evaluating the level of natriuretic peptides in HF patients.
Although the exact mechanism of VSA has not been elucidated, endothelial dysfunction is regarded as one of the most important underlying mechanisms.
Although atherosclerosis is commonly described as the presence of plaque obstructing the lumen of the conduit arteries, endothelial dysfunction is regarded as the initial step in the development of atherosclerosis and can be observed preceding structural atherosclerotic changes in the vascular wall or ultrasonic evidence of plaque [ 32, 33].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com