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The phrase "refrain in" is not grammatically correct and is not commonly used in written English.
It may be possible to use it in very specific contexts, but it would sound awkward and unclear to most readers. A better way to express the idea of refraining from something would be to use the verb "refrain" followed by the preposition "from." For example: "Please refrain from using your phone during the meeting."
Exact(58)
King had certainly thought about using the "dream" refrain in Washington.
The disappearance of the public intellectual has become a familiar, not to say wearisome, refrain in our declinist moment.
I will refrain in this arena but not give up the passionate fight for @realDonaldTrump's agenda.
That is a familiar refrain in Harlem.
It's a popular refrain in recent times.
Harvard is a refrain in "Steal this Menu".
This was already a familiar refrain in Song's lifetime.
This will be Putin's refrain in the coming days.
That is a common refrain in cable news these days.
The refrain in the Arizona Diamondbacks clubhouse has become familiar.
"Vote" has become a refrain in Mr. Obama's stump speeches lately.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com