Sentence examples for refractory forms from inspiring English sources

Although clinical trials have not confirmed a clear superiority of rituximab in SLE, observational studies have shown good response rates in severe SLE manifestations or refractory forms.

Vanast described NDPH as a headache that would improve without therapy, but as most headache specialists know, NDPH can be one of the most refractory forms of CDH to treatment.

We also show that the 3′-UTR CRP rs1130864 A allele carrier state is more prevalent among patients with rapid cycling, which is relevant since thyroid disorders and auto-immune abnormalities are associated with refractory forms of BD, in particular, rapid cycling (Chakrabarti 2011; Padmos et al. 2004), even though these two phenotypes were not correlated in our cohort.

Indeed, 30 40% of patients are considered to have chronic and refractory forms of MDD (Berton and Nestler, 2006).

In summary, we describe a collaborative research approach to the elucidation of the underlying cause of previously refractory forms of GRD.

Hematopoietic stem cell transplantation is the last treatment resort for refractory forms of EBV-related HPS, and in the case of EBV infection occurring in genetic forms of HPS [ 40].

It may be the reason for getting more refractory form of NDPH [15].

Autologous stem cell transplantation and melphalan have prolonged overall survival rates in patient populations, but most individuals eventually succumb to a refractory form of the disease.

Rapid cycling, defined according to DSM-IV as four or more mood episodes in any combination or order within any year in the course of the illness, is a severe and often treatment refractory form of bipolar disorder with tendency for more depressive than manic episodes [6], [7].

This refractory form predominates over all other forms of NB and has a poor prognosis, with an event-free survival at five years of only 30% [ 1, 2].

A major challenge in the treatment of prostate cancer, especially the hormonally refractory form, is the presence of genetic and cellular abnormalities associated with tumorigenesis.