Sentence examples for refractory expression from inspiring English sources
A structural description of the complete AdoMetDC/ODC bifunctional complex is lacking, mostly due to the refractory expression of this large protein complex in heterologous systems.
To determine if there was a change in expression in progression from hormone-sensitive to hormone-refractory disease a Wilcoxon signed-rank test was used to compare the hormone-sensitive expression score to the hormone-refractory expression score for each protein and each location.
To identify hormone refractory dependent expression changes MET_HR samples were scaled to the median across the non-refractory samples MET_HN.
To address this question, miR-125b-refractory retroviral expression constructs were made containing the coding region of TNFAIP3 or NKIRAS2.
Our surprising finding is that Xenopus tadpole brain is largely refractory to exogenous expression of HSF1.
Neural tissue in C. elegans has been previously shown to be refractory to gene expression knockdown by RNAi [18].
Finally, we consider in molecular terms why EC cells, but not their differentiated derivatives, are refractory to the expression of many viral genomes following infection.
These observations suggest that chronic METH might have caused additional epigenetic modifications that had rendered Crem expression refractory to the acute effects of the drug.
These yeast techniques also offer an easy method for profiling the drug sensitivity of uncharacterized Bcl-2 orthologs, including Bcl-2 relatives that are refractory to bacterial expression.
Two cancer data sets were used as applications to show the benefit of identifying condition/subtype-specificity, 1) a refractory cancer gene expression data with 113 cancer patient samples of 32 different tissue types [ 16], and 2) The Cancer Genome Atlas (TCGA) glioblastoma multiforme (GBM) gene expression data.
The ability to more potently direct NK cell-mediated cytotoxicity against refractory tumors through the expression of CAR is likely to contribute to the recent paradigm shift in cancer treatment.
