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The REFLEX study demonstrated that early treatment (i.e., following the FCDE) with s.c. IFN-β-1a significantly reduces the risk of FCDE conversion to MS, whereas the ongoing REFLEXION study will establish the long-term effects of administration of s.c. IFN-β-1a following an FCDE, allowing us to determine whether the benefits currently seen with early treatment persist.
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REFLEXION is an ongoing study and will continue to follow patients for at least 5 years after the FCDE.
Accompanying the Salomon work is "Reflexion," an installation by the French artist Christian Boltanski that suggests the ambiguity of visual experience and relates in some ways to Salomon's grand epic.
In REFLEXION, the ongoing extension of the REFLEX study, patients originally receiving placebo who had not converted to CDMS at 2 years were switched to s.c. IFN-β-1a t.i.w. and those receiving the study drug continued on their original regimen if they had not converted to CDMS [20].
All experiments performed in this study followed the recommendations of the "Comité National de Reflexion Ethique sur l'Experimentation Animale" of the Ministry of Higher Education and Research and were approved by Local Animal Care and Use Committee (approval n° 7I12).
Many years of work by think tanks Cercle d'Action et de Reflexion autour de l'Entreprise (CARE and Notre Algeriee Batie sur de Nouvelles idees (NABNI), producing a number of studies and proposals for economic reforms, can come in very handy to the Algerian government in this effort.
It is based on a reflexion on some emerging themes in the recent debate in urban studies, paying particular attention to the approaches that emphasize the fragmentation of public space and the presence of control strategies, highlighting the function of tecnologies and material elements of built environment.
Drew [ 28] emphasize that by keeping the contact with ones own intention to the phenomenon and by keeping a constant reflexion to identify and explain ones unique experience of the phenomenon, validates the study.
In another work, Knodel and Popescu [19] compared reflexion models and two other techniques (relation conformance rules, and component access rules) to assess their applicability on architectural conformance.
For all the self-reflexion of their work, they are a pair of buskers.
Recently, the Rebif Flexible Dosing in Early MS (REFLEX) study and its ongoing preplanned extension, Rebif Flexible Dosing in Early MS Extension (REFLEXION), demonstrated the benefits of early intervention with s.c. IFN-β-1a [19-21] [19-21]
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