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Chronic cough patients also underwent cough reflex sensitivity testing using citric acid.
BAL was performed immediately after cough reflex sensitivity in non-sensitized guinea pigs.
ONO1714 reduced the OVA-induced increase in cough reflex sensitivity only in sensitized guinea pigs, but it did not affect the normal cough reflex sensitivity in non-sensitized guinea pigs.
Although cough reflex sensitivity is increased after antigen challenge in actively sensitized guinea pigs, it is unknown whether the antigen-induced increase in cough reflex sensitivity develops in passively sensitized animals.
Whereas in OVA sensitized guinea pigs, BAL was performed 24 h after cough reflex sensitivity.
To evaluate cough reflex sensitivity in a population of young, healthy, male cigarette smokers.
Little is known about the normal ranges and repeatability of cough reflex sensitivity measurements, or the relationship of cough reflex sensitivity to other upper airway reflexes in subjects with chronic dry cough.
Results: Subjects treated with baclofen had a significantly higher cough threshold (diminished cough reflex sensitivity) than control subjects.
Conclusions: The results suggest that chronic therapy with baclofen diminishes cough reflex sensitivity in subjects with C-SCI.
Moreover, when reflex sensitivity was partially restored in SP-SAP animals, somatic stimulation failed to attenuate baroreflex bradycardia.
Increased stretch reflex sensitivity also may have influenced tracking performance during interactions with the unstable loads.
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