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At the start of each hour, after alignment in the pupillometer, four pupil light reflex measurements were recorded (2×488 nm; 2×610 nm).
The constant laboratory illumination (10 lux) and repeated hourly delivery of an equivalent stimulus energy for the pupil light reflex measurements allowed us to determine if circadian variation in ipRGC and cone photoreceptor activity was independent of environmental light.
From early on important insights into central components of hyperalgesia have been obtained in humans [ 6], from reflex measurements in experimental animals, for example [ 7], as well as from single neuron recordings in ventral- [ 8] and more importantly in the dorsal horn [ 9] of the spinal cord.
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Startle responses and prepulse inhibition of the startle responses were measured using an automatic startle reflex measurement system (O'Hara & Co).
The startle reflex measurement system (O'Hara & Co). was used to measure PPI.
A startle reflex measurement system was used (O'Hara & Co., Tokyo, Japan) to measure startle response and prepulse inhibition.
The room is electrically shielded and earth-grounded for H-reflex measurements.
Table 5 shows the results of the reflex time measurements.
Little is known about the normal ranges and repeatability of cough reflex sensitivity measurements, or the relationship of cough reflex sensitivity to other upper airway reflexes in subjects with chronic dry cough.
Because the majority of the CPA6 morphants were morphologically indistinct from uninjected controls, optokinetic reflex (OKR) measurements provided a direct assessment of the general integrity of the responsible central pathways as well as the motoneuron innervation of the eye muscle.
Therefore, deep assessment proposes the inclusion of a third technique to enhance its rigor: Startle Reflex Modulation Measurements.
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