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All data were entered into the screening database that was linked to the Osaka Cancer Registry OCRR) database with data reflecting incidence cases through December 2003.
These proportional reductions were then applied to French incidence data reflecting incidence prior to the implementation of HPV vaccination (screening only) at the national level.
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These proportional reductions were then applied to European incidence data reflecting incidences prior to HPV vaccination implementation.
Also, the study by Terada et al. indicated that pediatricians reflected incidence rates from 1/2 to 1/8 that of the general population their age.
Second, the variable time to seroconversion across individuals means that even if all samples were taken on the same date they reflect incidence at different times in the previous weeks.
We assumed that WNV incidence in blood donors reflects incidence in the general population.
Finally, we ascertained mortality not incidence, but this should not represent a major limitation since, with its high fatality rate, pancreatic cancer mortality would closely reflect incidence.
As one can see there is much higher number of lung cancer patients which likely reflects incidence of lung cancer seen in the general population.
We incorporated updated data from the widest possible sources of information, assuming that mortality reflects incidence for this fatal form of cancer.
These findings are unexpected, given that MCC is generally considered to be highly aggressive and lethal, and mortality would be expected to reflect incidence.
The overall RR for bladder cancer related to exposure to mineral oils was taken as a weighted average across these case control and population-based studies reviewed, and reflected incidence and mortality due to bladder and other urinary tract organs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com