Exact(1)
(2) Some of the remaining inconsistencies could be biologically grounded, reflecting breed structural variations.
Similar(59)
To reflect breed formation the demographic scenario consisted in three completely isolated populations separated t = 25 generations ago from an initial common population with an effective population of Ne = 5,000.
These were located in the transmembrane regions and the extracellular carboxy- and intracellular amino-termini of the protein and may also reflect breed-specific differences as the available sequence data comes from a Hereford animal whilst our data is from a Holstein Friesian animal.
Consequently, attempts to reconstruct the relationship between breeds based on their allelic composition [ 3- 5, 28, 29] are likely to have been heavily influenced by such random effects and may not necessarily reflect true breed history.
Any difference between the MAF distributions probably reflects a breed of ascertainment effect (i.e. the SNPs were discovered because they were the most common SNPs on these chromosomes in Holstein), which would lead to an excess of high MAF SNPs in one breed and an excess of low MAF in the second.
Accuracies of GEBV from ALL PE for the Limousin breed reflect that no pure-breed Limousin individuals were part of the training population.
In the region close to the drop ear associated SNPs there is very high heterozygosity in a heterogeneous sample of breeds, reflecting the presence of multiple SNPs with highly divergent frequencies between breeds.
No sweep regions were shared between indicine and taurine breeds reflecting their divergent selection histories and the very different environmental habitats to which these sub-species have adapted.
One possible explanation for why Golden Retrievers separate from non-Golden Retrievers in this analysis is that hierarchical clustering by breed reflected unique properties of genetic variants within the breed, rather than a particular influence of breed on tumor phenotypes.
The effective population size of all cattle breeds is known to have decreased in recent history and this may reflect initial domestication, breed formation or selection for breed specific production traits (beef or milk) [ 18].
The results obtained for the Brahman breed reflect the historical records on the formation of this breed, which indicate that a synthetic indicine population was created in the United States during the early 1900's by breeding indicine animals of the Nelore, Gir and Guzerat breeds imported mainly from Brazil to intensively upgrade the available taurine cattle from a base population [ 29, 30].
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