30– 33 The tumor that finally develops may reflect a selection of poorly immunogenic and/or immune-resistant malignant cells.
It may also reflect a selection of personality traits that liberal arts students may react more sensitively and emotionally to events and stressors than their counterpart students studying other subjects.
It can be speculated that these positive results may reflect a selection of patients with early stage cirrhosis with only minimally lowered thrombocyte counts, which were therefore regarded to be eligible to receive IFN.
As a result, one could assume that physicians are more likely to switch patients to NOAC therapy if they had to discontinue VKA therapy due to complications or risk factors for adverse events during VKA therapy, and, therefore, our cohort might reflect a selection of patients at high risk also for rivaroxaban discontinuation.
It is possible that a random acquisition of DNA methylation on single allele of these genes reflects a selection for reduced expression of these genes which may be relevant to the generation of imprinted genes during evolution [36].
One major concern regarding the methylation recovery observed in our system was whether the aforementioned DNA re-methylation was merely reflecting a selection attributed to the growth advantage of 5-Aza-dC-resistant cells.
Although our results showed improvements in the intervention group, this may reflect a selection effect of dental practices volunteering for the first round of the European Practice Assessment.
This probably reflects a selection bias of a clinic-based study.
Because clinical studies suggest that females require less ICU treatment in comparison with males [ 14], incorporating ICU patients may reflect a selection bias of females with reduced prognosis in comparison with the overall female population.
In the health care setting of the developing world, the presentation of patients to specialised RA clinics, of which there are few, is likely to be delayed, and our study cohort may therefore reflect a selection bias of patients seen in a tertiary setting.
