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This group postulated that the improvement in donor oxygenation at 4 h reflected clearance of neurogenic pulmonary oedema [3].
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HDAC inhibition resulted in decreased H3 acetylation at the promoter (likely reflecting clearance of the promoter; see Fig. 3h) and partial increase within the gene (Fig. 3a).
It is important to note, that sFasL was not detected by Western blot in the whole lysates from WT mice, possibly reflecting clearance from the eye or instability of the soluble form.
Rather, it might reflect clearance of the plasma membrane for caveolae occupied by cross-linked or aggregated receptors or ligands.
The levels of activity in the heart were similar at all time points to blood levels reflecting clearance of antibody from the circulation.
These observations may reflect clearance of treatment-sensitive regions of the tumour, but persistence of tumour volume consisting of intrinsically resistant cells, which subsequently give rise to disease recurrence.
He cited the lack of positive findings from occupational cohort studies in which individuals were exposed to much higher toxicant concentrations and suggested that at background levels serum concentrations might reflect clearance factors that are related to risk of diabetes through diet or other innate factors in addition to intake.
The ontogeny of UGT2B7 isoenzymes may have a one to one effect on low-extraction substrates as in this case, in vivo clearance closely reflects intrinsic clearance.
What emerged as the most striking observation in the patients we studied was the relationship between the kinetics of virus clearance, possibly reflecting antigen clearance, and the presence of antiviral CD4+ T-cell responses.
The decline in response thus, reflected parasite clearance and clinical cure.
The authors concluded that the EAA was superior to the LAL, even at low endotoxin levels and reflected hepatic clearance.
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CEO of Professional Science Editing for Scientists @ prosciediting.com