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Following the advent of the web, journals ceased to be important for readers but maintained importance for authors who wanted to get the reflected benefit of the Impact Factor (I will come to this poisonous issue later), which can play a major role in deciding their future as a scientific researcher.
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Practice and coverage indicators provided the hard benchmarks to assess success or failure, as they directly reflected benefits to the population.
Endpoints need to reflect benefit to patients, and show that changes in tumour size either in absolute terms (response and progression) or relative to control (progression) are clinically relevant.
In designing such criteria, individual components must be chosen and weighted such that a favourable score reflects benefit outweighing risk to a meaningful degree.
Whether this reflects benefit of withholding any nutrition, irrespective of the route, or more deleterious effects of more PN remains to be studied [ 64].
Relationships between Mayo scores and both PRO measurements were stable, in the right direction (reflecting benefit to the patient), and approximately linear.
Whether this reflects benefit of metformin, adverse effect of insulin, or difference between type 2 diabetic patients requiring the two agents cannot be deduced from the reported associations.
Hence, irisin reflects benefits of exercise and muscle activity.
"Their research and development spending is ahead of their peer group, but the company's financial results haven't yet reflected the benefit of the innovation".
Because traffic agents spend most of the day working alone, the findings reflected the benefits of an overall supportive atmosphere, Dr. Brondolo said.
"More than anything else," Mr. O'Neal wrote, "the quarter reflected the benefits of a simple but critical fact: we go about managing risk and market activity every day at this company".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com