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Access rates achieved in that study were high due to incentives provided within the study, and are unlikely to reflect usual practice; hence lower access rates are used in the decision model (Table 1, see also supplementary material).
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Pathologic examination of the aorta was performed in only half of the patients undergoing surgery, reflecting usual practice in Denmark.
To reflect usual clinical practice, all kinds of non-study pharmaceutical treatment are allowed, including changes prior to and after inclusion.
It is important to point out that to reflect usual clinical practice, providers, APP and surgeons, had access to the patient's medical file and previous imaging tests.
In order to reflect usual clinical practice and maximise generalisability, we do not control the use of postoperative analgesia, fluid management and other aspects of patient care.
In addition, the data in phase 2 were analysed on a per woman basis to reflect usual clinical practice, and women with HG CIN on any biopsy will be managed differently from those who do not have HG CIN.
The large population database of the study, with more than 850,000 people recorded, will increase considerably the external validity of the results and will reflect usual clinical practice at the Primary Care settings in the Spanish NHS.
The number of randomised trials included is small, and the findings of this study might reflect usual clinical practice until 2000 (date of the most recent randomised study in this review).
Nevertheless, the data recorded during this study reflect usual clinical practices.
Thus, these data are likely to reflect usual current clinical practice for managing cSSTIs in hospitalized patients in the US.
Because of the study design these data likely reflect usual current clinical practice for managing cSSTIs in hospitalized patients in the US.
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