Erzurum, an ethnic and religious hodgepodge in eastern Turkey, once described as The Rock by NATO, when it during the Cold War hosted the alliance's most south-eastern air base, reflects the backbone of popular support for Mr. Erdogan: conservative and nationalist rural towns and cities.
To pinpoint the backbone dynamic properties of the P56S MSP in aqueous solution and in the membrane environment, we acquired the heteronuclear NOE which reflects the backbone motions on the ps-ns time scale.
The distance between G16(H1′) and G18(H8) averages 7.2 ± 0.2 Å, consistent with the lack of connectivity at the G16-G18 step in the NOESY spectrum, and reflects the backbone stretch induced by intercalation of the DB[ a, l]P aromatic ring system.
The significant deviations in the spectral shapes in the amide I region (1700 1600 cm–1) between the wild type and H166L, which reflect the protein backbone conformational changes, indicate differences in conformational changes between the two proteins.
The different colors reflect the quantification of the backbone nodes (i.e., the "differential network backbone values") derived from the NPA algorithm that demonstrate the biological mechanism pertaining to xenobiotic metabolism.
The landscape of the area is being reshaped as the old uses that reflect the former economic backbone of the city, are displaced or replaced by new ones which are more related to the industry of entertainment.
Another way to reconcile the differences is to note that HDX data primarily reflect the stability of the backbone secondary structure.
Finally, on a personal note, I think chemical probing with DMS (revealing the accessibility of the Watson-Crick positions) would add very convincing evidence to the Shape data that reflect only the backbone.
The behavior of tubulin in this trajectory, as reflected by the backbone RMSD from the starting structure, was also very similar to that seen in the ATP trajectory.
Similar to the behavior of tubulin in our simulations of both nucleotide states, the kinesin transition was largely complete by 1 ns, as reflected by the backbone RMSD from the starting structure as well as the observed interactions in the atomic model itself (Video 3).
