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This may reflect regulation of mRNA through degradation or translation.
Many of the data sets used in our analysis reflect regulation under constant light or in light:dark cycles, where the lights-on and lights-off signals at dawn and dusk both participate in entraining the Arabidopsis clock [55], [56].
These may either reflect regulation through a non-consensus Spo0A-binding motif, or indirect regulation.
Transcriptional regulatory networks of mature tissues may not reflect regulation during early embryo development.
This lack of difference in mRNA may reflect regulation by post-translational processing and is an area of ongoing investigation.
Cluster III (p < 0.00001) share many genes with cluster I and II but reflect regulation of progression through meiosis.
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This difference reflects regulation.
Nonetheless, the expression of hypoxia-inducible genes (with the exception of Mt1/ Mtendednded to be enhanced in ZnT8−/− mice, possibly reflecting regulation of HIF1α by Zn2+ [ 46].
Note that basal levels of LC3-II could be detected even in the presence of IL-3 (0-h time point in Figure 1a), which reflects regulation of cellular homeostasis by autophagy.
It is consequently hard to argue that the individualized profiles, reflecting regulation along gene expression axes, does not influence each person's immune health to some degree whether this is clinically useful remains to be clarified.
The complexity of p53 degradation may reflect the regulation and integration of diverse p53-mediated signaling pathways.
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