As many of the comments are repetitive and often contain multiple themes, we manually analyzed and performed a bottom-up, inductive coding to identify and refine the underlying themes.
In further attempts to dissect the disease phenotype, gene expression profiles have been used to refine the underlying mechanisms in molecular subsets, to discover predictors of drug response and identify novel drug targets [6], [7], [8], [9].
I also moved back and forth between writing memos and drawing diagrams to realize where each category had a strong or weak relation to each subcategory and made attempt to refine the interrelationships underlying emerging processes in both tasks separately.
We observed dsx expression in most sensory neurons of the reproductive system, including a subpopulation of the previously characterized fru +/ ppk + neurons located in the uterus, further refining the sensory circuitry underlying the postmating switch.
Here we review the literature on spillover for refining the terminology, detailing the underlying mechanisms and identifying both the existing and needed methodological approaches to measure spillover.
While simulation and data transformation (e.g. graph theory measures) have been proposed to refine the understanding of the underlying function-structure relationship, the potential complementary and/or independent contribution of EEG and fMRI to this relationship is still poorly understood.
The addition of temporal measures and the correlation with other cognitive tests can refine the reasoning about the underlying processes of syntactic comprehension.
Nevertheless, a number of areas remain unresolved and warrant further investigation to refine our understanding of the underlying mechanisms of action and to optimize clinical SCT protocols.
Adequate reporting and connection between the individual centres exploiting these data will foster collaborative and comparative research studies throughout Europe for better patient care and to refine our understanding of the underlying mechanisms of action that may directly translate into optimized protocols for SCT in ADs.
We believe our ongoing and future studies, and those of others will provide refined mechanisms underlying the integration of HHR6 and FA pathways in maintaining genomic stability (Fig. 5).
