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If the objective is the selection of markers for refining mapping in an inter-specific cross, or for discriminating two or more species, the user can identify diagnostic markers (i.e. with species-specific allele range) with known genetic map location or not.
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Reifenberger, G. et al. Refined mapping of 12q13-q15 amplicons in human malignant gliomas suggests CDK4/SAS and MDM2 as independent amplification targets.
Refined mapping and YAC contig construction of the X-linked cleft palate and ankyloglossia locus (CPX) including the proximal X-Y homology breakpoint within Xq21.3.
For refined mapping we corrected [35], [36] for possible type I errors due to over-relatedness of parents by adding inbreeding loops to the pedigrees based on the relationships between parents determined by the PREST analysis (Table 2).
Refined mapping of the critical region of loss should help attempts to identify and clone the candidate gene.
a c, e, f, Local resolution evaluations of the full PTEX map (a) and the focus-refined maps of the upper/hexameric (b) and lower/heptameric (c) halves of PTEX in the engaged state, the full PTEX map (e) and the focus-refined map of the lower/heptameric (f) half of PTEX in the resetting state, calculated by Resmap56 and coloured according to resolution.
Several subsequent experiments to which Smoot made major contributions in instrumentation, including the recent Planck satellite, have refined maps of the CMB to the point that they now mark the first notch in a "cosmic ruler" used to measure the history of an expanding universe driven by dark energy.
In these analyses, locations of T. nigroviridis genes were identified first using the Genoscope map, and then verified with a recently refined map in the Ensemble database.
This interface includes procedures to initially place markers on a map and refine map order, as well as a number of utility routines.
It is possible that integrating W→S DAF skew into models of the evolution of recombination could help identify previously unrecognized hot spots and refine maps of recombination.
Where evidence for linkage was found, additional CAPS markers from the same chromosome regions were used to analyze individual F2 plants to refine map positions.
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