As a result, the detected foreground benefits the depth value refinement compared with the methods without foreground information.
Typically, better statistical performance is achieved by successive refinement compared to network multilateration, but convergence issues must be addressed.
It is observed that we achieve a higher injection rate with grid refinement compared to the original grid, which is consistent with the polymer rheology.
We show here that combining knowledge-based conformational sampling in RAPPER with molecular dynamics/simulated annealing (MD/SA) vastly improves the quality and power of refinement compared to MD/SA alone.
□ In this section, we present a numerical example to compare the different error estimators and demonstrate the advantages of adaptive mesh refinement compared with uniform refinement.
Despite BCML's lack of refinement compared to the currently available alternatives, it provides additional functionality, and it highlights a possible solution to problems that are now arising when representing pathways.
(A ) Gain in R free of ensemble refinement compared with re-refinement using phenix.refine, (B ) number of structures in the final ensemble model, (C ) optimum relaxation time, τ x, (D ) optimum p TLS and (E ) optimum T bath plotted as function of resolution of the dataset.
As expected, for a given number of DOF a more accurate solution can be achieved by adaptive, local h-refinement, as compared to global refinement in a fully matching setting.
To determine the effects of the above refinements, we compared signals detected during the 12 weeks after implementation with those that would have been detected had HLMoriginal still been in place.
The solutions obtained with and without adaptive mesh refinement are compared in terms of solution improvement and computational cost.
