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Further refinement will be necessary before the technique is ready for people, but it could also generate other organs.
More research and technical refinement will be necessary to investigate normal human skeletal development and to identify MR imaging characteristics of skeletal abnormalities.
However, incomplete knowledge of PQ's active metabolites and their pharmacokinetic profiles means that our model of PQ's killing action is only a gross approximation, and further refinement will be necessary as we learn more about PQ.
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Thus, further marker discovery and technological refinements will be necessary to improve test performance [ 114].
Further technical refinements will be necessary to definitively demonstrate or rule out functional orthology between PACT and R2D2.
It may be, however, that further refinement of the model will be necessary to accurately predict channel diameter.
11 A reevaluation of the clearance of BMS-911543 followed by refinement of the PBPK model will be necessary when human ADME results for BMS-911543 become available.
Fine-grained analyses linking specific profiles of strengths and deficits with specific patterns of symptom emergence will be necessary for further refinement of screening and diagnostic instruments for ASD in infancy.
Refinement of these mathematical and economic models will be necessary to help optimise screening and vaccination programmes in the future.
Refinements in the pretreatment procedures and database will be necessary to further improve identification of Nocardia.
Although there are clear advantages to the bone-anchored system, further development and refinement of the device and the surgical technique will be necessary in order to optimize the clinical results and to minimize the risk of complications.
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