Sentence examples for refinement target from inspiring English sources
Here, we present a very different approach that also achieves the goal of improving structure quality; in this case by incorporating terms responsive to hydropathic interactions into the X-ray refinement target function using the empirical HINT (Hydropathic INTeractions) forcefield [11].
For the FREALIGN refinements, four rounds of refinement and reconstruction were initially performed, using successively higher resolution cutoffs for the refinement target (20 Å, 15 Å, 12 Å, 10 Å).
Also, the SphereGrinder score (Kryshtafovych et al., 2013) was used for the assessment of local accuracy of refinement targets in CASP9 (MacCallum et al., 2011).
A refinement of target identification at the central tracker is based on the local track IDs, which resolves conflicting identities in the local tracks of the same target.
The second cycle employed positional and ADP refinement with target weights optimization and water update was carried out with these complete models.
Molecular imaging continues to impact diagnosis and staging of lung cancer, but refinements in target volume definition and eventually prescribed dose definition are needed.
Future studies investigating the in vivo delivery of siRNAs to tumors using nanogels, and the effect on chemosensitization will aid in the refinement of targeted siRNA delivery for treatment of ovarian cancer.
In future it is anticipated that further refinements in targeting the elimination or suppression of the GVHD reacting T cells should be selective enough to preserve the important graft-versus-leukemia effect which contributes to the cure of malignant diseases by allogeneic stem-cell transplantation.
The plots illustrate the convergence of post-refined parameters, target functions, and quality indicators during post-refinement over five macrocycles.
This neurodevelopmental paper reports on the transcription factor Zic2 as critical regulator of visual target refinement.
The development of the nervous system is a time-ordered and multi-stepped process that requires neural specification, axonal navigation and arbor refinement at the target tissues.
