Exact(2)
The development of stimulation techniques of the sensory and motor functions in a rehabilitation context is likely to improve and help restore postural function while the refinement of testing techniques improves descriptions of dysfunction of the postural function.
ZEBET is dedicated to all three facets of the 3Rs, that is, replacement, reduction, and refinement of testing in animals, which have been incorporated into the EU Directive 86/609 (Fig. 1).
Similar(58)
Although there remains ongoing debate about the relative merits of IHC and FISH testing for routine clinical practice (Sauter et al, 2009) and whether further refinement of HER2 testing such as phospho HER2 analyses (Frogne et al, 2009) will add additional value remains to be seen, this series was based on current guidelines for HER2 testing (Ellis et al, 2000; Walker et al, 2008).
With regard to the "3 Rs" (reduction, replacement, and refinement) of animal testing and the European regulation of chemicals [Registration, Evaluation, and Authorisation of Chemicals (REACH ], alternative testing strategies are needed in order to refine and reduce animal experiments and allow faster and less expensive screening.
Refinement of laboratory testing strategies for WNV surveillance may help use resources and build broader public health laboratory capacity for arboviral and other CNS infections.
Generate test cases from B implementation modules: since B implementations represent more closely the tested code, the ability to also generate test cases from them would reduce the abstraction gap and make the process of refinement of the test cases easier.
Identifying cognitive biomarkers, specifically and directly regulated by neurofibromin, would enable smaller pilot studies to demonstrate proof of principle and dose refinement by testing whether promising preclinical treatments normalize pathophysiologic processes in human patients before expensive randomized controlled trials are conducted.
Nevertheless, further refinement of the test design especially in relation to possible loss of ambiguity problem is necessary.
In this case, however, the B implementation of each module was available as reference for the refinement of the test data (transformation of abstract to concrete data).
Therefore, development of transplantation source animals with reduced PERV activity, development and refinement of clinical tests for PERV transmission, and accurate preclinical risk assessment, are much needed.
Further investigation and refinement of the test would be valuable.
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