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This algorithm is meant to be an intermediate refinement of draft genomes prior to further fine scale refinement at the sequence level.
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Further refinement of the draft sequences of the pig genome will elucidate the duplication of genes occurring in the Sus genus.
The available draft genome sequence of CS represents an important aid to common wheat structural and functional genomics investigations [ 49], and continuous refinement of the draft sequence with transcriptome data should enhance its utility.
Refinement of the draft sequence of the pig genome will reveal the precise locations on the pig genome of the loci generating those transcripts that we cloned but that were not mapped, or that we mapped only on unplaced scaffolds.
This manuscript describes the development process for the QOL PCD Adult version which included the following phases: 1) literature review and expert panels; 2) open-ended interviews with patients in in UK, USA and Canada; 3) item generation; 4) cognitive testing; and 5) refinement of the draft measure.
MKC, JMG and DRE were all involved in the development and refinement of subsequent drafts.
Second stage comprised of semi-automatically refinements of the draft reconstruction through gap analysis.
Further refinements of the draft assembly and targeted re-sequencing may help to determine the full-length sequence of these partial photoprotein genes.
All authors contributed to further refinement of the first draft and the revised manuscript.
SPP did the literature search, refinement of results and drafted the paper.
It was also used in the creation and refinement of the Italian Heavy Draft, the post-World War II improvement of the Schleswig horse, and the creation of the early 19th-century Ardennes.
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