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A "Find Clusters" functionality allows the detection and refinement of data clusters in a semi-automatic way.
They will remain a challenge for further improvement and refinement of data filtering and processing.
From the several plant genomes sequenced in recent years, only Arabidopsis has really benefited from a comprehensive monitoring and a real refinement of data generated automatically.
Refinement of data collection methods in future research on emergency service involvement with care homes is needed to fully address decision-making in relation to outcomes (i.e. whether residents are treated on-site or conveyed to hospital) and understand potentially emerging issues surrounding non-conveyance of older people with dementia resident in care homes.
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Further, future efforts to develop predictive models of anopheline cell signaling responses, based on iterative construction and refinement of data-based and literature-based knowledge of the MAP kinase cascades and other networked pathways (reviewed in [ 65]), will ultimately be necessary to elucidate the "master signaling regulators" in these biomedically important insects.
Further, future efforts to develop predictive models of anopheline cell signaling responses, based on iterative construction and refinement of data-based and literature-based knowledge of the MAP kinase cascades and other networked pathways will facilitate identification of the "master signaling regulators" in biomedically important mosquito species.
FM contributed in various ways in the work reported in this paper including; refinement of methodology, data collection, data analysis, inputs to various versions of manuscript, editing and approval of final version.
HW and KW were involved in the development and refinement of the data collection tools, interpretation and presentation of the data and carried out the data analysis.
YJ participated in data collection, and contributed to the refinement of the data.
Full molecular replacement and refinement of the data to 2.7 Å, using a more conservative data cut-off (I/σI=2), showed that the electron density did not change, but automatic rebuilding failed, indicating that the weak data contained significant information and that any errors in their measurement were sufficiently reduced by the use of maximum likelyhood refinement.
Figure 3 Rietveld refinement of synchrotron data.
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