To overcome these limitations, further refinement of GO classifications for the Oct4 correlated genes was performed by manual curation of a wide variety of databases such as NetAffx, GeneCards, Ensembl, Stanford Source, Bioinformatics Harvester, and PubMed (Supplemental Table S2).
Tree topology, the large sequence variation among fungal APs, and the apparent functional diversification suggest that an amendment to update the current A1 AP classification based on a comprehensive phylogenetic clustering might contribute to refinement of the classification in the MEROPS peptidase database.
refinement of the classification results using the knowledge of inactivity zones.
A refinement of this classification was made by Leung et al. [16].
Because of its gradual increase in heterogeneity across all subtypes this module is particularly well suited for further refinement of tumor classification.
The neonatal outcomes include overall mortality at 28 days of life (primary outcome), mortality in subgroups of isolated and non-isolated cleft groups, hospitalization days, and refinement of syndromic classification in the retrospective group.
1 It has not only served as both a validation and a refinement of available classification schemes but has also offered new diagnostic tools that have led to significant improvement of diagnostic accuracy.
Therefore, the 'Nzumoigne', 'Kupulik', 'Foulah' and 'Vudu papua' cases reveal that the stringency of these triallelic combinations allows refinement of subgroup classification and that these allelic combinations might be used as easy keys for assigning accessions to subgroups.
The resultant CHOCIP data will be a rich information source that can be applied to the development or refinement of patient classification systems and associated resource allocation models for community health and outpatient care services.
Hence, literature confirmation and refinement of toxicity classification was an important step in our method and acted as a validation step to filter out potentially false signals generated from the pharmacovigilance data.
