Further marker studies and refined selection criteria are necessary for more specific in vitro CSC isolation.
Perhaps the most frequent one is to refine selection criteria to exclude patients unlikely to respond: those with right bundle branch block, severe kidney insufficiency, and high burden of scar.
In an effort to improve on the current standard, PSA-derived markers, PSA kinetics, and patient characteristics including genomic profiling and imaging have all been investigated to refine patient selection with variable results.
Although additional study is warranted both to demonstrate equivalence and further refine selection criteria, two professional societies have published guidelines for APBI with useful selection criteria (Table 4) [ 28, 29].
Together, our findings provide evidence for the use of this newly identified predictive gene signature to refine the selection of patients with wild-type p53 tumors and increase the likelihood of response to treatment with p53 HDM2 inhibitors, such as NVP-CGM097.
Thus, it remains unclear whether such excess in fact exists; further, more refined, experimental attempts with selection of RNA aptamers for such amino acids would be most welcome.
To refine feature selection, the FFS (Forward Feature Selection) procedure based on the result of IFS was used.
Peter Kindel, who previously ran the cheese department at Artisanal, is working with Rob Kaufelt, the owner, to refine the selection of 200 cheeses.
Given the combination of epidemiologic and socioeconomic factors unique to Latin America versus other regions, data from defined ethnic groups will help clinicians to refine the selection of the best possible treatment options for patients with RRMS.
Sometimes it helps refine your selection criteria.
A method to refine seed selection for boosting rice yields under SRI method of rice cultivation.
