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Sometimes a refined picture of a disease's history has invalidated clinical practices based on apparently reasonable assumptions.
Condemning the comics as crudely drawn, sensational and subliterary, librarians saw the genre as the very antithesis of the aesthetically refined picture books and illustrated gift books that they championed.
For example, he said, in this year's drill, officials deciding whether and where to order evacuations will use a new computer program with a much more refined picture of how long it takes to move people.
To get a more spatially refined picture, we also performed a calculation of attraction basins at thirty spatial positions in the range 37%-57%EL 37%-57%ELcd ensemble normalized by the basic method.
This has resulted in both a more refined picture of the genetic architecture of many growth traits and the cloning of several of the genes that underlie plant QTL.
These two genome sequences thus afford a refined picture of the potential of Methylobacterium for physiological flexibility and adaptation to specific environmental constraints within a conserved genomic framework, and provide the basis for renewed, systems level experimental investigations.
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That means not just refined pictures on the walls, but refined walls, too.
By subjecting the non-cytosolic fraction to various pre-treatments we have refined our picture of the pronecrotic factor: firstly, it is resistant to protease inhibitors and to cysteine proteases but sensitive to serine proteases.
More recent resequencing efforts have refined this picture by cataloguing over 8 million SNP alleles across 16 inbred strains [41] and genetic maps of similar densities were further imputed in 49 strains [42].
The work of Hildebrand et al. (20) has refined this picture.
This has refined our picture of the spatio-temporal occurrence of epigenetic marks, yet our mechanistic understanding on how their deposition is regulated remains limited.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com