Because occupancy and B-factor are strongly coupled in a traditional refinement, the occupancies of bound ligands and ions are typically set to unity, while the corresponding B-factors are refined in a single-structure refinement.
"People think of Chinese food as somehow less refined than western cuisine," he says, "but that's not true: it's just refined in a different way".
The optimal transformation is hierarchically refined in a subdivision framework.
Petrol was first refined in a building on Hepscott Road, E9.
And the work doesn't stop with the existing algorithm: It is honed and refined in a continuous improvement process.
The monologues are created extemporaneously, without a script, the material shaped and refined in a nightly evolution.
The annotation of the genome was refined in a multi-step approach, including modern bioinformatic pipelines, transcriptome and proteome data.
Their focus was refined in a series of workshops on what was known, unknown, and unknowable (KUU) about the subject.
A conversation can be had – a decision made, a plan refined – in a matter of minutes, no matter where in the world the two parties happen to be.
Unlike Wallander, Morse, Rebus, Poirot or even Holmes, Saga was not honed and refined in a series of novels, but created for the screen by Hans Rosenfeldt.
For this reason, Tennessee is a proving ground for the principal change in the proposed bankruptcy law, now being refined in a Senate-House committee.
