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These models provide a platform for in silico experiments that help us better understand mechanistic sources of uncertainty, generate refined hypotheses, and interpret empirical observations.
Refined hypotheses are developed based on a national environmental and human health information system, giving an overview of research related to human health diseases suspected to be caused by chemical stressors.
Such method limitations might explain the high incidence associated with both diabetes and kidney disease and reinforce the need to consider these findings as highly refined hypotheses to be tested by other methods (12 ).
A famous case of this approach was that of the grouse (Lagopus lagopus) research unit on the heather moors of the Scottish Highlands where initial hunches framed research which led to formulation of hypotheses that were then tested yielding more refined hypotheses for the on-going investigation.
Actually the presence of the reinforcement requires the development of a specialized treatment, that is presented in the paper, with the purpose of exploring the dependence of the solution on more or less refined hypotheses about the masonry material in the presence of reinforcement.
This type of finding proves the potential of in silico analyses able to produce highly refined hypotheses, based on vast experimental data, to be tested further and more efficiently.
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Moreover, in some cases, animal models and cognitive neuroscience approaches have illuminated the underlying neurobiology subserving behavioral performance on such measures [ 59- 62], permitting more refined hypothesis testing of genetic variants that influence impulsivity.
Common sense must be maintained, which allows us, for example, to experiment just to help develop and refine hypotheses (Basili et al. 1986).
"It explains the pattern of migratory and sedentary populations on the globe and probably refines hypotheses on many aspects of monarch biology".
Although large-scale implementation of management regimens within an experimental design is difficult, long-term case studies provide opportunities to improve learning and develop and refine hypotheses.
A defining aspect of both fields is the design/build/test/learn cycle, or the use of iterative rounds of testing modifications to refine hypotheses and develop best solutions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com