These databases provide specific metabolic roles for genes acting as a highly refined function prediction.
We expected that by parsing genes based on coexpression similarities, more refined functions would be condensed within modules, revealing enrichments for more specific processes.
The high degree of conservation between human and chimp POP2 suggests that POP2 refined these functions at some point following the divergence of macaques with purifying selection acting at that point to completely conserve POP2 prior to the divergence of humans and chimps (~ 6 mya).
It is informed by a function-based outlook on language (Givón, 1993; Halliday, 1994) and a sociopragmatic framework (Fetzer, 2004; Gumperz, 1992) supplementing and refining function-based results with context-based parameters, that is production format and recipient design, genre and media frame.
The ability to distinguish between orthology supported by all domains and orthology supported by a subset of the domains only would be helpful to improve the quality of ortholog assignments and refine function inference across orthologs.
To refine UGT73C6 function in the context of functional redundancy it was therefore aimed to generate plants deficient in the expression of both UGT73C6 and UGT73C5.
In practice, this principle led us to redefine the importance of a residue in terms of the importance of its epistatic interactions with neighbors, yielding better annotation of functional residues, motivating experimental validation of a novel functional site in LexA and refining protein function prediction.
In this work, we improve PPSampler by refining scoring functions and a proposal distribution used inside the algorithm so that predicted clusters are more accurate as well as the resulting algorithm runs faster.
He insists that D-Day could have been a rout but for the fact that by mid-1944, British, American and Canadian warriors — from the top down — had transformed their organization into a smoothly functioning apparatus, refined their means of gathering intelligence and designed the now-famous "bodyguard of lies" that misled the Nazis about when and how the Allies would invade Europe.
Therefore we assume that the likely SPL7-interactome consists of largely functionally redundant components that probably contribute more to refine SPL7 function, rather than to its activation.
The DCA decomposes the non-convex objective function in to the difference of two convex functions, and iteratively approximates it through a refined convex objective function.
