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It's refined from a plant in the Amazon jungle and we had it shipped in from California in a briefcase.
Some horseshoe-crab experts consider fifteen thousand dollars to be too low an estimate, considering the amount of LAL that may be refined from a quart of blood.
"We got through the process of getting the franchise agreement set up, we got the model refined from a financial point of view," he says.
In fact, there are no numbers (this post is adapted and refined from a reply I posted to James's comment), or no solid ones anyway.
The PyMTL framework encourages a philosophy of "modeling towards layout" in which a microarchitecture is incrementally refined from a high-level functional-level model, to a timing-approximate cycle-level model, to a bit-accurate RTL implementation.
In addition, an alkaline phosphatase that was active at low temperatures was refined from a species of Shewanella (Ishida et al. 1998; Tsuruta et al. 1998).
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For decades afterward, he championed SoundSpel, a simplified English spelling system he had refined from an earlier model.
For this study, the Q-sample was refined from an earlier concourse, a collection of statements comprised of experiential, theoretical and evidence-informed viewpoints, collated by two of the authors of this study.
The predictive power of these models has been refined from sequence analyses of NRPS A-domains with known specificity combined with examples of crystal structures of A-domains [ 9- 11], thus identifying amino acid residues crucial for A-domain specificity.
Coal and oil, extracted and refined from the earth, are a different story.
Thorium is estimated to be about three to four times more abundant than uranium in the Earth's crust, and is chiefly refined from monazite sands as a by-product of extracting rare earth metals.
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