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Vermeer wouldn't have the huge following that he does if, instead of women, he had painted bowls of fruit or highly refined flower pictures, as so many Dutch artists of his era did.
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Data were not available on the conditions for which the antibiotics and homeopathic products were used, but the dataset was refined to exclude creams, ointments, Bach flower remedies and Arnica as they are not used to treat infections.
Strikingly, when all neurons in the retina were forced to present the apoptosis-triggering Flower Lose isoform, the excess neurons persisted and the neuronal network was not refined [ 31 ].
The intriguing interaction between flowers and their pollinators is the reason for the evolution of most refined coloration signals (e.g., Lloyd and Barett [138]).
So refined.
Very refined.
"Shanghai is more refined.
It was very refined".
"This is more refined.
Smooth, refined and spicy.
Understated, discreet, refined.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com