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The truth probably lies somewhere between these different interpretations, where stream of influences mix with experiences and beliefs and create a general direction that actors tend to follow and refine through compromise and consensus.
However, it likely does compromise structural models refined against low-resolution structural data where atomic positions are less well defined.
Typically, all nonbonded interactions are modeled with a simple quadratic repulsive term in CNS, which does not compromise structural models refined against high-resolution X-ray data where atomic positions are well defined solely by experimental data.
A low density region which - for whatever reason - is refined to a high level does not compromise our results.
That mellowing and compromise is echoed in the sound: the squalling guitars have been refined a little and the band sound more minimal and electronic than ever.
In the past five years, however, more refined freezing methods have been developed and made available to some women whose fertility has been compromised by chemotherapy or premature menopause.
So refined.
Very refined.
It was very refined".
"This is more refined.
Smooth, refined and spicy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com