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This motivates us to test which dataset (refined or original) has higher expression coherence.
Under such a setting, coherence subsets were further refined using spectral clustering methods.
In the second stage, the spatial coherence of these initial labels is refined by a Conditional Random Field (CRF) or a second stage LRC that combines them with neighboring-patch and global-aggregate contextual features.
We further refined this by using the notion of gene coherence; in doing so we discovered that a number of genes are strongly incoherent, behaving erratically across the studies.
So refined.
Very refined.
"Shanghai is more refined.
Smooth, refined and spicy.
Theyre not notably refined".
It is refined.
It was refined.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com