Next, a refined cluster-association matrix RM is generated from BM by estimating new association values in R M x i, C j ) if B M x i, C j )=0.
In this paper, we take a refined co-association matrix, which is originally used in ensemble clustering, as an initial similarity matrix and transform it by path-based measure, and then apply it to VAT.
Nonetheless, the study refined patterns of associations of related lipid traits at already known loci and provided new insights into the complexity of lipid metabolism.
White bread consumption may be a marker of an unhealthy diet, although an adverse association of refined carbohydrates with risk has been noted before (Chatenoud et al, 1999).
Thus, including other measures of socioeconomic position (occupational class and/or income) would have allowed for a more refined analysis of the association between socioeconomic position and access to specialized prescribing.
By applying an original competing risks approach and considering AKI as a time-dependent variable, we likely provided a refined estimation of the association between AKI and mortality as compared to previous reports.
The KIR 'Bx' genotype has previously been associated with increased relapse-free survival after unrelated haematopoietic cell transplant [ 44] and the discrimination of 'AB' from 'BB' genotypes will make it possible to perform a more refined investigation of this association, including the determination of the underlying genetic model.
Our population included only women who were OP treatment naïve, and our outcome was OP treatment initiation, not the combination of OP treatment initiation or BMD testing; thus, our study likely provides a more refined assessment of the association between pretreatment GI events and OP treatment initiation.
In population studies, Western-type dietary pattern components such as red meat, high-fat dairy and other sources of saturated fat, and refined carbohydrates show positive associations with biomarkers such as CRP and fibrinogen.
The role models and goal models for instance are further refined to provide a clear association between agent roles and lower level goals to permit associating problem solving capabilities (using PSM libraries) and system goals in the early stages of the system design.
