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To refine these two sets of genes, we incorporated protein networks at this stage.
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We will review these main aspects raised by parents in order to refine these three profiles.
Only five of these had previously been identified as containing multiple independent variants (Chr3p12, Chr4q22, Chr8p21, Chr11q13 and Chr17q12); however, our analysis helped to further refine these five regions and identified one additional previously unknown hit at Chr17q12 within the promoter region of HNF1B.
Robotic technique allows the surgeon an approximated 10-fold improvement in visualization of the surgical field, thus refining these two options.
We further refined these three areas by constructing separate indices for social network subdomains of family, neighborhood and church, and emotional and instrumental subdomains within social support, for a total of six separate indices.
"Willie"'s jumping, spinning and bonking machanisms were refined in these two levels.
Rather, policymakers will need to consider a combination of national direction with increased local autonomy, to develop mechanisms that would enable policy implementers to evaluate and refine the balance between these two perspectives in a systematic and evidence-based manner over time.
Through discussion within the evaluation team (PB, JS, VSH) we developed coding categories that reflected emerging themes and refined these through three rounds of coding and modification (see Table 1 for final coding categories).
Apple refined those four lines over the course of seven years.
Further biochemical and mutagenesis studies would be necessary to refine the functional differences between these two opsin subtypes.
JMH was responsible for refining the two clinical care protocols.
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