Sentence examples for refine the structure of from inspiring English sources

The SAR analyses will guide us to further refine the structure of the thieno[3,2-d]pyrimidine derivatives to achieve optimum anticancer activity.

Furthermore, RNA-seq can detect genes expressed at low levels and refine the structure of transcripts (Wang et al. [2009] Wilhelmm and Landry [2009]).

The presence of pseudo-symmetry [16, 17] is sometimes a problem when trying to refine the structure of a material that undergoes a subtle phase transition – unit cell doubling for example can lead to highly collinear combinations of atom position parameters; the only data about the specific differences between the average and doubled cell are present in the weak superstructure reflections.

Our results refine the structure of the Math5 transcription unit, explore the concept of an intronless gene, and provide a cautionary lesson for PCR-based studies of RNA processing.

Synchrotron X-ray diffraction data allowed us to solve and refine the structure of the complex at 1.45-Å resolution (Table 1), much higher than previously obtained for the CaM-CnA-CBD complex (between 1.86 and 2.6 Å).

Furthermore, our data refine the structure of the human ErbB4 gene, clarify that juxtamembrane (JM) splice variants of ErbB4, JM-a and JM-b respectively, are characterized by the replacement of a 75 nucleotide (nt) sequence with a 45-nt insertion, and demonstrate that there are four alternative exons in the gene.

We identify two time-independent difference maps, from which we refine the structures of the corresponding intermediates.

We begin with some observations on the structure of von Neumann regular right self-injective rings which will help us in refining the structure of endomorphism rings of ({mathcal {X}} -automorphism invariant and ({X}} -automorphismomorphinvariantandant modules.

We subsequently refined the structure of the substrate-binding model by means of energy minimization, indicating that slight movements of residues I167, N173 and F212 enable the enzyme to adapt to 3-quinuclidinone (Figure 4c).

We have also refined the structure of the full-length CC to 12.4 Å resolution.

Our analyses have refined the structure of the latter two clusters, revealing some hitherto undescribed loci, plus some novel divergent homeobox loci that are in, or close to, the Obox array.