Sentence examples for refine the associated from inspiring English sources

Once this association had been replicated, resequencing would be necessary to identify exonic and promoter SNPs to refine the associated haplotype.

We also showed that by using multi-populations it is possible to refine the associated cis-effect DNA regions.

Finally, we aimed to refine the associated region and identify causative variants by targeted resequencing.

This helped us to refine the associated region down to 2.8 kb, where a functional variant might be located.

At the same time, they refine the associated proposals and decide whether they could be implemented from this level or they need approval from the Management Group.

To refine the risks associated with different classes of ATM variants, and to examine the molecular pathologic characteristics of ATM-positive tumors, we genotyped 76 rare ATM variants in 2,570 breast cancer cases and 1,448 controls.

Based on these data, we refined the region associated with prostate cancer risk to a 15 Kb LD block and revealed strong signatures of selection in multiple human populations and, possibly, other primate species.

Chromatin conformation assays were also used to refine the 11q13 locus associated with breast cancer to CCND1 (38) and the 2q35 locus to IGFBP5 (32).

Employ a series of population- and family-based studies of severe malaria phenotypes to refine the risk estimate associated with T1264G.

These results suggest that routine testing of early onset PrCa cases for germline BRCA1 mutations would further help to refine the prevalence and risk associated with BRCA1 mutations and may be useful for guiding management options.

These results suggest that routine testing of early onset PrCa cases for germline BRCA2 mutations will further help to refine the prevalence and risk associated with BRCA2 mutations and may be useful for guiding management options.