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Our realisation that bidirectional motion is principally driven by diffusion also refines substantially our interpretations of the experiments assessing the behaviour of RNPs at MAPs and microtubule ends.
It should be noted that the deposited crystal structures of catalase obtained by conventional X-ray crystallography were refined to substantially higher resolution.
We substantially refine his result, showing how the size of the maximum family depends on λ.
Thus, the evidence to date suggests that molecular profiling can substantially refine cancer prognosis, perhaps well beyond what is possible with other clinical indicators.
While BSA (step 3) provides a rough chromosomal location, it is still necessary to substantially refine the map position of the mutant of interest for the eventual cloning of the gene.
The scale of the microstructure is substantially refined as compared with composites produced using other recently developed powder processing techniques.
This principle has been substantially refined by subsequent experimental and theoretical work and now provides an equally powerful functional account.
Granularity is substantially refined as block matrix operations are carried out in a true element-wise approach.
The sizes of reinforcement particles in the FSPed composite coating were substantially refined from 12.2 μm to 4.4 μm due to the severe stir effect of the tool at a rotating speed of 1400 rpm.
However, this panel could be substantially refined in the future given the prevalence of recurrent copy number aberrations in driver genes seen in Fig. 1, and the recurrent promoter methylation in lung cancer (Belinsky 2004) which is recapitulated in ctDNA (Mishima et al. 2015; Warton et al. 2016).
Our model presents a detailed scenario for the timing and scale of the initial migration to the Americas, substantially refines the estimate of New World founders, and provides a unified theory for testing with future datasets and analytic methods.
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