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They also have a "refine" option after your first search, which further narrows the results set (something Technorati really needs to add).
Nucleotide sequences were translated to protein sequences and aligned first with ClustalW [60] using the default settings then with the refine option in MUSCLE [61].
Each individual LCB was aligned further by using the program MUSCLE, without using the refine option.
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All alignments were subsequently refined with the refinement option in MUSCLE version 3.7 [ 35] [V].
But while the military has been developing and refining options for the White House for months, the discussion appears to have taken a new turn, officials say, in the struggle to determine whether the suspected use of sarin gas near Aleppo and Damascus last month was a prelude to greater use of such weapons.
Nintendo Refines Options For Parents [destructoid].
This serves as an introduction to the detailed discussion on the preferred refining options for the various cuts.
Phil Stride, head of London Tideway Tunnels at Thames Water, said: "Since the consultation closed we have been refining options, including reducing the number of sites required, and identifying alternative sites.
Not only does our resource conveniently integrate eleven different prediction databases in one place, it allows users to choose which combinations of databases they would like to consider – refining options by database or by database characteristics – when selecting prediction data.
Complex queries can be performed through the advanced search page, which incorporates a free text box and refining options for database types, resource categories, programmatic access methods, ontologies and minimum information checklists.
Then, the occupancy was refined for each individual NO using the grouped occupational refinement option in CNS.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com