The use of cyclophosphamide has been refined, however, employing strategies to reduce exposure and cumulative toxicity.
The information on the salt regulated root-developmental genes was further refined by employing the rich spatial transcriptomic resources that are available for model plant Arabidopsis.
Although parameter values were chosen within reasonable ranges for mouse skin, future models could be refined by employing recent compressive measurements of mouse skin (Wang et al., 2013).
Control of these functional task phases could be further refined by employing a hand tracking algorithm in order to classify and recognize each movement phase and thus automatically select the appropriate stimulation pattern by implementing temporal and spatial synergies.
In the second stage, the nodes refine their position estimates employing a decentralized information filter.
Even Margaret Thatcher sought extra help to refine her brand, famously employing a vocal coach to lower the pitch of her voice.
We calculated 100 independent structures that we refined in a water shell with the program CNS 1.21 (Brunger et al, 1998; Brunger, 2007) using a water-refinement protocol successfully employed to refine a large set of NMR structures calculated with CYANA (Nederveen et al, 2005).
Army officers who have recently returned from yearlong duty in Iraq applauded the doctrine, but said its methods were nothing new to field commanders, who have been employing and refining such tactics for months.
Analysis is at the U.S. petroleum refining sector national-level employing an aggregated notional refinery model (NRM), with the aim of estimating the efficacy of efficiency improvements for reducing emissions.
Al-Amoudi and co-workers refined the technique by employing cryo-electron microscopy in human epidermis.
In terms of the 3Rs (reduce, replace and refine), studies which employ only reward-based outcomes have important welfare implications, as they avoid the need to use aversive training methods (Mendl et al., 2009).
