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"This scanning technology will allow us to refine diagnosis," said Dr. Joseph Fins, chief of the medical ethics division of New York-Presbyterian Hospital/Weill Cornell hospital, "but it also creates this never-never land, these paradoxes between what patients are demonstrating clinically and what they manifest on the images".
Early diagnosis via imaging techniques is especially desirable to refine diagnosis, guide intervention, and monitor response to therapies [ 3].
These novel findings have thus the potential to significantly refine diagnosis and possibly alter management of these cancer patients.
Screening for molecular markers or somatic mutations known to be specific of particular tumors appears as a promising tool to refine diagnosis.
Several studies evaluated in various settings the usefulness of biomarkers to understand pathophysiological processes, to guide therapy or to refine diagnosis.
More sophisticated non-invasive imaging techniques are required that can accelerate and refine diagnosis, guide intervention and monitor response to therapies that may stabilize lesions and prevent future atherothrombotic events [1].
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Conclusion: Our data suggest that 8p23 allelic loss is associated with poor prognosis in head and neck squamous cell carcinoma and could be useful refining diagnosis of these tumors.
Prognostic factor research is important as it helps in refining diagnosis, taking clinical and therapeutic decisions, enhances the design and analysis of intervention trials and helps to identify targets for new interventions that aim to modify the course of a disease.
To determine patterns in amino acids (arginine, GABA, glutamate and glutamine) and the diamine (agmatine) in plasma and cerebrospinal fluid (CSF) of mild and severe preeclampsia compared to control patients, using capillary zone electrophoresis to generate methods for refining diagnosis and prognosis and shed light on the pathophysiological mechanisms of preeclampsia.
In addition, the HMDC includes the Australian Refined Diagnosis Related Group (AR-DRG) code for each admission.
Patients were stratified in four All Patient Refined Diagnosis Related Group (APR-DRG) severity levels.
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