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The referred module is used at the operational level for recording data on the performed operations, evidencing several flaws compared to its purpose as an integrated management tool.
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It consists of the DECOB modules which remain after having applied an automatized ranking-based filtering procedure to the DECOB modules which results in a reduced number of modules, referred to as DECOBRA modules.
These are referred to as module 1 and module 2 for simplicity.
The modules were denoted by numbers from zero to 55 and prefixed with "ME" referring to "module eigengene" [ 50].
In the following sections we present the results of implementing this approach, to which we shall refer as module algorithm, based on a number of microarray experiments.
4) The Klf7 discussion: In the results referring to module number 2 we now conformed to the standard terminology, where 'effect size' refers to difference between strains, and 'significance of effect' refers to the P value for these differences.
We refer to modules in a meta-network of modules as meta-modules.
The correlations between ALS status and the module eigengene of the Blue module (referred to as MEblue) were r = 0.48 (p = 3.6 × 10-5), r = 0.37 (p = 2.6 × 10-3), and r = 0.41 (p = 6.2 × 10-7) in data sets 1, 2, and 3, respectively.
We therefore merged these two modules and referred to the resultant module as M1.
To define a representative module expression profile (referred to as the module eigengene), we summarized the (standardized) gene expression profiles of the module by their first principal component.
To define a representative module expression profile (referred to as the module eigengene), we summarized the (standardized) gene expression profiles of the module eigengene (= first principal component).
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