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Although there is an increase in the mention of at least some statistical design parameters in phase II cancer clinical trials over a 5-year period in these selected cancer journals, the use of referenced methods is still short or often inadequate.
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Quantitative approaches using the tCho peak integral, SNR and referencing methods are discussed below.
The visual evaluation of the proposed and reference methods is shown in Figures 6b. and 7b.
A comparison of both reference methods is carried out with the µFTS from 0.35 µg/s to 35 µg/s.
A combination of the Hitschfeld-Bordan and surface reference methods is used to correct the attenuation effect in radar returns.
No indication of the comparison method's analytical performance, bias, imprecision, total error [ 8], or its traceability to higher reference methods is provided.
Below follows condensed details of how the reference methods were used.
● Test and reference methods were well described concerning technique and implementation.
These reference methods are expected to accelerate uptake of the technique and facilitate development of commercial TERS probes.
Quantitative comparisons of the reference methods are shown in Figures 8 and 9. Average PSNR for tested schemes are given in Table 1.
For method development and validation, reference methods are needed to demonstrate the relevance of measured data.
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CEO of Professional Science Editing for Scientists @ prosciediting.com