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The analyses of the single-frequency probe data included only those trials which could not be reinforced by food (i.e. including a subset of reference trials).
Consistency in analyses can also be applied to determine if trials conducted in specific regions have outcomes consistent with reference trials conducted for regulatory approval in other countries [ 41].
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The objective was to develop a method to determine the power of a trial, based on minimal information from a previous (reference) trial.
Taking GCT as a reference, trial-by-trial comparisons of iPDC and cMVGC, respectively, confirm the pattern of higher FP for the former compared to a pattern of FP, below 1%%, for cMVGC with or without correction (See Figs. 13, 14).
The reference trial for this economic evaluation assessed the efficacy of IPT-SP on malaria prevention during pregnancy, and the results showed that SP was highly efficacious in preventing clinical malaria 30 days after each administration [22].
A static reference trial was recorded to adjust the marker set to individual anatomy and to evaluate valgus knee angle.
The dose of S-1 in this study was 80 mg/m2 per day, which is higher than doses used in the reference trial that combined S-1 with oxaliplatin.
β0 j and β1 are as in Model A, with λ k once again the hazard rate in the control group of the reference trial.
Table 2 summarizes the probabilities for each of these health outcomes, derived from the reference trial results (Merck Sharp and Dohme Ltd, data on file, 2011).
For time intervals, k = 1,..., K, we now have: (7) h 0 k (t ) = λ k where λ k represents the constant hazard rate in the k th interval for the control group, in the reference trial.
33 Use of aprepitant was associated with lower health care resource utilization compared with the comparator regimen, mainly due to fewer hospitalizations in the aprepitant group in the reference trial.
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