The functionality was demonstrated by calibration with different reference substances.
The toxicity results of reclaimed water were converted into the equivalent concentrations of the corresponding positive reference substances (EQC).
The chromatographic peaks of 14 investigated compounds in samples were successfully identified by comparing their retention time, UV spectra and TOF mass data with the reference substances.
For that purpose, a set of reference substances preconized by the Organization for Economic Cooperation and Development (OECD) guidelines was used.
Accuracy and reliability are analysed by comparison with a reference QT correction method (Holzgrefe) from experiments performed with reference substances terfenadine, thioridazine and sotalol.
The results were predicted using a new method based on the generalized corresponding states principle (GCSP) in which properties of two reference substances were used to predict the superheat limits of the fluids studied.
The database approach consists basically of three steps: measuring reference substances to generate a database, measuring unknown or difficult samples and using the database for the identification of these samples.
Six reference substances (formaldehyde, alpha-hexylcinnamaldehyde, fragrance mix, thimerosal, mercaptobenzothiazole and phthalic anhydride); all mild to moderate skin sensitizing chemicals, were assessed in a study, which compared the use of 3 and 9 induction applications.
This study aims to compare the test results of LLNA: BrdU-FCM produced in BALB/c mice with those in CBA/J mice for 18 reference substances, including 13 sensitizers and 5 non-sensitizers, listed in OECD Test Guideline 429.
After measuring the manuscripts, we compared these results with reference substances.
Indacaterol maleate and glycopyrronium bromide reference substances were kindly provided by Novartis (Basel, Switzerland).
