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The typical reference procedure involves distillation followed by pycnometry, which is comparably labour-intensive and therefore expensive.
Satisfactory results were obtained for uric acid determination in 24 h-urine samples compared to a reference procedure.
Subjects treated their hands with the reference procedure (n-propanol, 60%) for 3 min or the product (crossover design).
Sterillium was more effective than the reference procedure at 3, 2 and 1.5 min (immediate and sustained effect).
The proposed procedure offers additional advantages over the reference procedure [14] in that the former is more sensitive with good accuracy and precision.
The FC-Index was determined according to the reference procedure for wine analysis [24] using a commercial FC reagent (Merck, Darmstadt, Germany, No. 1.09001.0100).
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The FTIR method has been previously validated and gives data comparable to the densimetric reference procedures [38].
The flow-through infrared device is much easier to handle than typical reference procedures, while time-consuming sample preparation steps such as distillation are not necessary.
To make sure that Bayesian reference procedures do not bias the data analysis in an undesirable manner, it is important to study their frequentist properties.
Aiming to access the accuracy sample were also analyzed employing reference procedures and no significant difference at 95% confidence level were observed for the four analytes.
The present study aims at the analysis of reference procedures and tools available for the analysis of the risk in the transportation of dangerous substances in the light of the Viareggio accident.
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