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Beginning in 1986, he oversaw the development of WordNet, an electronic reference databank intended to help computers understand human language.
In this case, 800 blood samples were to be part of a new, national mitochondrial DNA database intended as a reference databank for the forensic community and for research into mitochondrial DNA variation DNA we inherit from our mother.
In D. melanogaster (Table 3), when using only one clustering method, the GROUPER databank delivered the annotation closest to that obtained with the BDGP reference databank in terms of genome coverage and copy number.
Food and fluid item selections were made from a reference databank listing the nutritional composition of more than 1300 generic foods.
Food item selections were made using a database of component pictures based on the French Data Centre on Food Quality (Centre d'Information sur la Qualité des Aliments; CIQUAL) table, a reference databank of the nutritional composition of more than 1300 generic foods.
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We annotated both genomes with the TEannot pipeline [24] using the reference databanks cited above.
We therefore propose three indices for measuring the quality of de novo databanks, with respect to reference databanks.
So, rather than using the reference databanks directly, we first constructed, for each genome, a "knowledge-based" databank comprising one consensus sequence per reference TE sequence, based on its genomic copies (see Methods).
Similarly, we were able to identify putative new non autonomous TEs in the D. melanogaster and A. thaliana genomes that had all the essential features of TEs but were nonetheless absent from the reference databanks.
The number of clusters obtained by the de novo approach was much higher for GROUPER and RECON than the number of TE families present in the reference databanks (BDGP or Repbase Update).
Finally, we compared the annotations obtained with de novo libraries and reference databanks, by calculating genome coverage and TE copy number, together with sensitivity and specificity, in terms of nucleotide overlaps (Figure S3).
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